Serum Total Bilirubin Level and Prevalent Lower-Extremity Peripheral Arterial Disease

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Serum Total Bilirubin Level and Prevalent Lower-Extremity Peripheral Arterial Disease

Background—Bilirubin, with recently recognized antioxidant and antiinflammatory activity, has emerged as a candidate for atheroprotection. We hypothesized that higher levels of bilirubin would reduce susceptibility to peripheral arterial disease (PAD). Methods and Results—We analyzed 7075 adults with data available on the ankle brachial index, serum total bilirubin level, and PAD risk factors i...

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Serum total bilirubin level and prevalent lower-extremity peripheral arterial disease: National Health and Nutrition Examination Survey (NHANES) 1999 to 2004.

BACKGROUND Bilirubin, with recently recognized antioxidant and antiinflammatory activity, has emerged as a candidate for atheroprotection. We hypothesized that higher levels of bilirubin would reduce susceptibility to peripheral arterial disease (PAD). METHODS AND RESULTS We analyzed 7075 adults with data available on the ankle brachial index, serum total bilirubin level, and PAD risk factors...

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Lower Extremity Peripheral Arterial Disease

Eight to 12 million people in United States have PAD (Allison et al. 2007). Only ~10% of patients with PAD have classic intermittent claudication (IC), ~50% have atypical leg symptoms and ~40% are asymptomatic (Hiatt 2001). Its prevalence significantly increases with age; 12 – 20% of those above the age of 65 years suffer from PAD (Ostchega al. 2007). The prevalence of PAD is similar in men and...

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Peripheral Arterial Disease, Foot Ulcers, Lower Extremity Amputations, and Diabetes

Dr. Edward J. Boyko is Professor at the University of Washington and Staff Physician at the Veterans Affairs Puget Sound, Seattle, WA. Dr. Matilde Monteiro-Soares is an Investigator at the Center for Health Technology and Services Research (CINTESIS) and an Instructor in the Department of Community Medicine Information and Health Decision Sciences (U753-FCT), Oporto Faculty of Medicine, Oporto,...

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lower extremity arterial calcification as a predictor of coronary atherosclerosis in patients with peripheral arterial disease

conclusion peripheral arterial calcification is significantly correlated with cad extent in patients with pad. peripheral arterial calcification can be a useful marker for predicting multivessel-cad. results lecs in multivessel-cad were significantly higher than those in nonsignificant cad (10.0 ± 5.8 versus 4.0 ± 3.1, p < 0.001). lecs significantly correlated with ccs (r = 0.831, p < 0.001) an...

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ژورنال

عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology

سال: 2008

ISSN: 1079-5642,1524-4636

DOI: 10.1161/atvbaha.107.153262